The aberrant activation of JUN may result in the inhibition of T cell activation (TCA), and since MS is a chronic debilitating disease of the central nervous system, it is primarily mediated by T lymphocytes with specificity to neuronal antigens in genetically susceptible individuals (Baer, Colon-Moran & Bhattarai, 2018). This evidence concerns the gene JUN and myeloid sarcoma.