ITGBL1 and posterior cortical atrophy: We also attempted to include only one gene (ITGBL1) and one circRNA (circ_0062019), which were the best biomarkers for the diagnosis of PCa in our previous publications, and found that when the expression of ITGBL1 and circ_0062019 was considered along with the three DelncRNAs, the AUC was 0.957 (Figure S3C), the sensitivity was 93.3%, and the specificity was 92.3% (Table S2), which were significantly improved compared to three lncRNAs.