In this study, we investigated the association between the expression of lncRNA LAMTOR5-AS1 and aggressive cancer (Gleason score 8–10, p < 0.05) (Table 4) and found that lncRNA LAMTOR5-AS1 expression was higher in the less aggressive PCa (Gleason score 6–7; GS6-7) than in the aggressive PCa (Gleason score 8–10; GS8-10), yet its expression in GS8-10 was higher than in non-cancer tissues (p = 0.023) (Figure S2), which indicated that LAMTOR5-AS1 might be useful in the early diagnosis of PCa. The gene discussed is LAMTOR5; the disease is cancer.