RHOA and cancer: For other genes that are not included in the Sanger database, we also confirm their important role in cancer-related biological processes through literature verification, such as ETS1 (Watabe et al., 1998; Fujimoto et al., 2004; Zhang et al., 2014; Li et al., 2015) and RHOA (Lee et al., 2015; Zeng et al., 2015; Sun et al., 2016) in hallmark “Activating Invasion and Metastasis”.