Notably, KISS1, TIMP2, MMP11, IGFBP1, and EGFR have been reported to be involved in the metastasis of gastric cancer (Guan-Zhen et al., 2007; Kou et al., 2013; Wang et al., 2017; Wang et al., 2018; Sato et al., 2019). The gene discussed is IGFBP1; the disease is gastric cancer.