One receptor for TNFSF13B, TNFRSF13B, was among the genes significant in the trachea challenge by line interaction at 6 dpi (Deist et al., 2017b) and was differentially expressed between the Fayoumi and Leghorn chickens in the lung in both non-challenged birds and birds challenged with avian influenza (Wang et al., 2014). This evidence concerns the gene TNFRSF13B and avian influenza.