During follow-up, 19 (63.3%) patients with lung adenocarcinomas with mutated CTNNB1 and 259 (48.5%) patients with lung adenocarcinomas with wild-type CTNNB1 experienced a relapse, and 10 (33.3%) and 111 (20.8%) patients died, respectively. The gene discussed is CTNNB1; the disease is lung adenocarcinoma.