CTNNB1 and neoplasm: Age (p = 0.851), tumor size (p = 0.256), lymph node status (p = 0.184), pathologic stage (p = 0.322), and the presence of pleural invasion (p = 0.459) were similar between lung adenocarcinomas with CTNNB1 mutation and lung adenocarcinomas without CTNNB1 mutation, but the former group tended to have more female patients (p < 0.001) and more smokers (p = 0.019) (Table 2).