HLA-C and neoplasm: He shared his fascination for the MHC with his laboratory members, with whom he investigated a variety of topics in the MHC field, including the regulation of HLA expression in tumor cells (4, 5), the association between HLA alleles and diseases in Southern Italy (6, 7), the influences of MHC class I (MHC-I) on tumor killing by NK cells (8), and the cytokine-mediated regulation of MHC-I expression (9).