Interestingly, several of these RA risk SNPs have been annotated as eQTLs located in H3K4me3 peaks in memory T cells (i.e., FCRL3, CD83, ANKRD55, IRF5, BLK, IKZF3, TRAF1, and IFNGR2). The gene discussed is IRF5; the disease is rheumatoid arthritis.