Irrespectively, infection of Ad-h-elafin-treated mice with either IAV or PAO1 exhibited increased inflammation, as assessed by BAL total inflammatory cells, neutrophilia (Figures S2A–F), increase in cytokine and antimicrobials levels (Figures S2G–N), protease activity (Figures 9E–G,J), and tissue injury (Figure 9L). The gene discussed is PI3; the disease is infection.