OAS1 and infection: However, cells treated with CM of P. aeruginosa strain PAO1 (CM-PAO1) showed a significant decrease in the induction of both genes after infection with hRV and RSV, which was most pronounced after 14 h of infection compared to control medium [fold induction (FI) of MX1: 285 vs. 6, p < 0.001; FI OAS1: 49 vs. 1, p < 0.001; Figure 1A].