In addition to their emerging autoreactivity, CLL-related transcription factors (LEF-1, NFAT2), innate-defense components (TLRs), chemokines/cytokines (Ccl3, Ccl4), migration elements (CXCR5), and Myc expression were also shared. The gene discussed is LEF1; the disease is B-cell chronic lymphocytic leukemia.