In addition to their emerging autoreactivity, CLL-related transcription factors (LEF-1, NFAT2), innate-defense components (TLRs), chemokines/cytokines (Ccl3, Ccl4), migration elements (CXCR5), and Myc expression were also shared. Here, NFATC1 is linked to B-cell chronic lymphocytic leukemia.