Using the MC38 immunogenic colon cancer model, BMP7-expressing and control tumors were grown in the flanks of C57BL/6 mice treated with anti-PD-L1 or isotype control antibody, and examined for CD8+ T cell infiltration at 5 weeks post-inoculation (Supplementary Figures 8, 9, 12). Here, BMP7 is linked to malignant colon neoplasm.