Significantly, nine genes (C1orf141, CALU, CCDC136, FGF2, LOC101927051, MAP4K4, MPZL3, PAPOLG, and SH3BP1) were found to be associated with more than one disease in the VEGAS2 analysis, although these genes had never been reported to be associated with any autoimmune/autoinflammatory disease in previous GWAS. The gene discussed is PAPOLG; the disease is Autoimmunity.