While CEACAM3 transcripts and protein have only been detected in human granulocytes and myeloid leukemia cells, the other closely related CD66 antigens are either widely expressed on epithelial and hematopoietic cells (CD66a/BGP/CEACAM1 as well as CD66c/NCA-50/CEACAM6) or exclusively expressed by mucosal epithelial cells (CD66e/CEA/CEACAM5) (17–19). The gene discussed is CEACAM3; the disease is myeloid leukemia.