GBP1 and colorectal carcinoma: That GBP1 expression correlates with both inflammatory bowel disorder and decreased growth of colorectal carcinomas suggests that GBP1 acts in a similar manner in epithelial cells as it does in endothelial cells to decrease proliferation and inflammation-induced apoptosis (40, 41, 43, 44), which has profound implications for mucosal immunity and treatment.