STING1 and infection: Infection with DENV induces an antiviral immune state in the host cell through various pattern recognition receptors (PRRs) including Toll-like receptor (TLR)3, TLR7, retinoic acid–inducible gene I (RIG-I), and stimulator of interferon genes (STING) (Loo et al., 2008; Tsai et al., 2009; Sariol et al., 2011; Aguirre et al., 2012; Green et al., 2014).