INS and gestational diabetes: The protein expression of MFSD2a was significantly lower in maternal blood from both GDM groups (Control 3.54 ± 0.50a, GDM-diet 0.89 ± 0.17b, GDM-insulin 1.60 ± 0.42b, p < 0.001; Figure 1A), which was in agreement with the significantly lower level of MFSD2a previously reported by our group in placental tissue obtained from the same cohort of GDM patients (Control 0.91 ± 0.08a, GDM-diet 0.56 ± 0.07b, GDM-insulin 0.49 ± 0.046b, p < 0.001) (23).