CAT and cancer: Since the half-life period of CAT mRNA is rather long (about 42 h in human cell and 30 h in saltwater clam Meretrix meretrix), some unidentified redox sensitive proteins can bind to the 5′ UTR of the CAT mRNA to regulate its translational rate and plus at the protein level, as observed in rat PC12 cancer cells exposed to H2O2 (Haque et al., 2012).