SOD1 and amyotrophic lateral sclerosis: Treatment with fisetin reduced intracellular ROS levels, motor neuron loss and improved motor activity and survival rate in three different hSOD1-related mutant models of ALS (Drosophila expressing hSOD1G85R, hSOD1G93ANSC34 cells and transgenic mice hSOD1G93A) (Wang et al., 2018) (Table 1).