Low levels of reduced glutathione (GSH) in erythrocytes (Babu et al., 2008) and in the motor cortex (Ikawa et al., 2015) of patients with ALS, a systemic pro-inflammatory state (increased levels of IL-6 and IL-8) and an impaired antioxidant system (Ehrhart et al., 2015) have been highlighted. This evidence concerns the gene CXCL8 and amyotrophic lateral sclerosis.