For instance, miR-96 is upregulated in the retina of streptozotocin-induced diabetes rats (Wu et al., 2012) and in the plasma of type-2 diabetic patients (Yang et al., 2017), while miR-96 is downregulated in the RHO-mouse retina, a model for common form of inherited blindness (Palfi et al., 2016). Here, RHO is linked to type 2 diabetes mellitus.