However, this reaction can lead to a greater level of response described as gliosis, presenting as high levels of GFAP, which is detrimental to retinal tissue and exacerbates neuronal death, resulting in an increase in the retinal and vitreal levels of inflammatory factors, such as IL-6, while also decreasing levels of neuroprotective factors, such as CNTF (Bringmann et al., 2009). The gene discussed is IL6; the disease is Gliosis.