Among them, multiple mutations in the leucine-rich repeat kinase 2 (LRRK2) gene have been correlated to late-onset autosomal dominant PD (Kumari and Tan, 2009; Hernandez et al., 2016), accounting for up to 13% of familial PD cases and have been detected in 1–2% of idiopathic PD cases, making LRRK2 the most commonly linked PD gene. Here, LRRK2 is linked to Parkinson disease.