Whereas many studies have characterized LRRK2 gain-of-function models of PD in the rodent and insect (Liu et al., 2008), only one previous study has validated the Drosophila LRRK2WD40 as a model of PD (De Rose et al., 2016), showing that LRRK2WD40 mutants displayed features of PD including motor disability, reduced life span and mitochondrial damage (De Rose et al., 2016). This evidence concerns the gene LRRK2 and Parkinson disease.