HLA-DRB1 and Alzheimer disease: Using the GTEx database, we further corroborated that the polymorphism of rs9271058 was associated with HLA-DRB1 expression levels in several brain regions, which is consistent with the relevance between HLA-DRB1 and the pathogenesis of AD in previous GWAS results (Lambert et al., 2013; Wang et al., 2017).