Zhang et al. (2016) could not corroborate this association in the northern Han Chinese population. No studies have yet been conducted to assess the relationship between SNP rs17125924 within the FERMT2 gene and AD susceptibility in the Asian population. We provide evidence that the G-allele at rs17125924 located within the intronic regions of FERMT2 is a risk factor for AD and is particularly prominent in APOE ε4 carriers. The gene discussed is APOE; the disease is Alzheimer disease.