SLC1A2 and Huntington disease: A well-established HD phenotype in humans and mice is the loss of the astrocytic glutamate transporter GLT1 (also called EAAT2) (Arzberger et al., 1997; Liévens et al., 2001; Behrens, 2002; Shin et al., 2005; Faideau et al., 2010; Cao et al., 2019), which is probably due to transcriptional inhibition in the presence of mHTT (Bradford et al., 2009).