ABL1 and brain injury: It is intriguing to speculate that the early lack of effect on vascular morphology seen in our study could be related to downstream effects of Gleevec on BCR-ABL on Wnt/β-catenin cascades (Cilloni and Saglio, 2012) which we have previously reported is involved in late vascular remodeling following traumatic brain injury (Salehi et al., 2018a).