Reportedly, the kinases Akt, PKA, and p90 ribosomal S6 kinases (RSK/p90‐RSK/S6KA) can mediate tumor‐promoting EphA2‐S897 phosphorylation (Miao et al, 2009; Zhou et al, 2015; Barquilla et al, 2016). Here, RPS6KA2 is linked to neoplasm.