We observed that MUFAs were positively associated with CHD risk in contrast to results from a previous meta‐analysis.12 It is possible that these associations could also be reflecting underlying hepatic de novo lipogenesis activation, which is related to increased blood triglycerides, ectopic fat deposition, and insulin resistance.40, 41 The association of circulating SFAs with CHD risk was attenuated when adjusting for other fatty acids (model 2). Here, INS is linked to coronary artery disorder.