AMH and obesity due to melanocortin 4 receptor deficiency: Nutritional status and obesity may affect the synthesisof AMH, as some studies have reported a decrease inAMH levels in obese women, indicating a negativecorrelation between AMH and BMI, while othershave not mentioned a correlation between nutritionalfactors, body mass index (BMI) and AMH (14, 15).The prevalence of obesity is more than 50% in patientswith PCOS, leading to IR and increased insulin levelsin these patients.