The results showed gradually elevated expression of p-NF-κB, p-c-FOS, and p-c-JUN from normal subjects to patients with mild/moderate asthma to patients with severe asthma (p < 0.01 severe asthma vs. normal; p < 0.05 severe asthma vs. mild/moderate asthma) (Fig. 2b). The gene discussed is JUN; the disease is asthma.