When quantified in two representative PCa cell lines (LNCaP and PC3), most transcripts were upregulated in both cell lines compared to normal prostate epithelial cells (PrEC) except for NACA (downregulated in both cell lines), BRD3 and EPCAM (decreased in PC3 cells), and HDAC6 (downregulated in LNCaP cells) (Fig. 1d). This evidence concerns the gene HDAC6 and posterior cortical atrophy.