SOD1 and amyotrophic lateral sclerosis: Symptoms of ALS were reported at the age of 72 years and the disease rapidly progressed for 2.5 years52, compared to two reported patients carrying G93D-SOD1 mutation only, previously described as slow progressing ALS mutation (Onset ranged from 45–71 years and disease progression ranged from 4 years to 22 years)53.