MBL2 and systemic lupus erythematosus: Garred et al. 59 were the first to describe a higher frequency of thrombotic disease in SLE patients with MBL low-producing genotypes and this analysis was limited to arterial thrombosis in a later study by ∅hlenschlaeger et al. 55, while Calvo-Alen et al. 57 restricted their analysis to CVI.