After univariate analysis (Supplementary Table 2), variables with p < 0.05 were further evaluated using Cox model multivariate analysis, which indicated that low LDLRAD4 expression, advanced TNM stage, and advanced T stage and M stage were statistically significantly associated with the poor prognosis of CRC patients in terms of both CSS and DFS (Supplementary Table 3). Here, LDLRAD4 is linked to colorectal carcinoma.