Given the negative correlation between the expression of lncRNA LDLRAD4-AS1 and LDLRAD4 and the metastasis suppressor role of LDLRAD4, we sought to uncover the mechanism by which lncRNA LDLRAD4-AS1 promotes CRC metastasis by analyzing its role in regulating LDLRAD4. Here, LDLRAD4 is linked to colorectal carcinoma.