In the logistic regression analysis, Treg levels at 48 h were independently associated with good functional outcome at 3 months (OR 3.5; 95% CI: 1.9–7.8; p < 0.0001) after adjustment by age, previous history of hypertension, dyslipemia, atrial fibrillation, leukocyte counts, glucose and fibrinogen levels, high- sensitive C-reactive protein levels, basal NIHSS and cardioembolic stroke. The gene discussed is CRP; the disease is cardioembolic stroke.