Gonçalves et al. studied SNVs of NOS2 C−1026A (rs2779249) and G2087A (rs2297518), NOS1 (see Section 2.4.7 on “Migraines” regarding NOS3) and VEGF in 150 women with migraines in comparison with the control group consisting of 99 healthy women from Brazil. This evidence concerns the gene NOS2 and migraine disorder.