NOS2 and ischemic stroke: In a meta-analysis of six studies performed in the USA, Europe, and China, Wang et al. analyzed the association of NOS2SNVs (see Section 2.3.6 on “Ischemic Stroke” regarding NOS2) and NOS3SNVs (−922)A>G(rs1800779), (−690)C>T(rs3918226), and 298Glu>Asp (rs1799983) with a risk of IS in 3550 patients after an ischemic stroke and 6560 controls;no associations were detected [57].