Yan et al. studied 588 patients with IS and 557 healthy controls for associations of SNVs of NOS2 Leu608Ser (rs2297518), NOS3 (see Section 2.4.5 on “Ischemic Stroke” regarding NOS3), andGCH1 and CYBA with a risk of IS. Here, NOS2 is linked to ischemic stroke.