CMTM7 and obesity due to melanocortin 4 receptor deficiency: However, to our knowledge so far, no studies have been carried out about the relationships between the CMTM7 rs347134 polymorphism, the odds of general overweight/obesity or central obesity, and obesity-related anthropometric, physiological, and biochemical indicators, with a concurrent research also of their possible interactions with dietary, activity, and sleep assessments.