Interestingly, CXCR4 protein expression in microsatellite unstable CRC cell lines was detected only in Lovo cells, which represents 1 of 6 (17%) MSI tumors assayed; but CXCR4 was detected in 2 of 3 (67%) of MSS tumors assayed: HT29, SW480 cells. This evidence concerns the gene CXCR4 and colorectal carcinoma.