In addition, CXCR4 overexpression promotes tumorigenesis and its expression and activity are associated with cell proliferation [4,5,6,7,8], invasion [8,9,10,11,12,13], migration [8,14,15,16,17,18,19,20], inflammation [21], angiogenesis [22], and metastasis [23,24,25,26,27,28,29,30] in several cancer models. The gene discussed is CXCR4; the disease is cancer.