One of them revealed overexpression of the CXCL13 gene in active demyelinating lesions areas, the presence of the CXCL13 protein both in perivascular and parenchymal inflammatory infiltrates and elevated levels of CXCL13 in the cerebrospinal fluid (CSF) of patients with relapsing-remitting MS [33]. Here, CXCL13 is linked to relapsing-remitting multiple sclerosis.