In the present study, we investigated the role of a novel lncRNA ARAP1-AS1, which was suggested to be up-regulated in BRCA (breast invasive carcinoma) tissues by GEPIA In the present study, we revealed that ARAP1-AS1 exerted a pro-tumor function in BC, evidenced by cell proliferation and migration was restrained by ARAP1-AS1 knockdown, in line with its tumorigenic role previously identified in bladder cancer [16]. The gene discussed is PTGDR; the disease is breast cancer.