AFP and metastatic malignant neoplasm in the lymph nodes: Based on multivariable analysis, the prognostic factors for OS were older age (HR 1.736, 95% CI [1.396–2.157], p < 0.001), lymph node metastasis (HR 1.406, 95% CI [1.093–1.808], p = 0.008), surgical intervention, lower AFP level (HR 0.757, 95% CI [0.587–0.976], p = 0.032) and histologic type (Table 4).