AIF1 and infection: After the PAMs 3D4/21 cells were infected with CSFV-Shimen for 48 h, the DGE data showed that AIF1 expression was higher in infected cells than in the control PAMs (Fig. 1A), indicating that CSFV Shimen infection upregulates the transcription level of AIF1. Analysis of the basic characteristics of porcine AIF1 is shown in Fig. S1.