In the multivariate analysis using the Cox proportional hazard model, age > 55 years (HR: 1.78, 95% CI: 1.11‐2.88, P = .018), the presence of hepatitis (HR: 2.27, 95% CI: 1.14‐4.55, P = .020), time to recurrence >2 years (HR: 0.34, 95% CI: 0.21‐0.58, P < .001), serum AFP level at recurrence >20 ng/mL (HR: 1.79, 95% CI: 1.13‐2.84, P = .013), and treatment allocation (HR: 0.54, 95% CI: 0.33‐0.88, P = .014) were evaluated as significant factors (Table 3). Here, AFP is linked to hepatitis A virus infection.