Although many lncRNAs display highly lineage and cell type-specific expression pattern, we observed an increased expression of several lncRNAs dysregulated in a broad range of solid tumors, such as MIR31HG, which regulates senescence, as well as CYTOR (LINC00152), PVT1, HOXA-AS2 and SNHG12, which can regulate various cancer hallmarks25,28,46,47. This evidence concerns the gene PVT1 and cancer.