Sequencing of all 14 RASopathy‐associated genes in the 505 patients in the validation cohort identified 11 (2%) patients with disease‐causing variants (Table 2) and 15 (3%) patients with a VUS (n = 11) or VUS‐likely benign (n = 4) (Table S2) in the NF1 or SPRED1 genes. The gene discussed is NF1; the disease is RASopathy.