In previous reports on ADSNHL hearing loss, the progression rate for the POU4F3 gene was 0.5–0.9 dB/year41, that for MYO6 was 2.0 dB/year45, and that for ACTG1 was 2.0–6.0 dB/year46, and the results in this study suggests that the rate of hearing loss progression caused by EYA4 may be relatively mild. Here, ACTG1 is linked to hearing loss disorder.