ALOX15 and gastric cancer: Exosomes isolated from CAFs treated with cisplatin (Cis-CAF exos) or paclitaxel (Pac-CAF exos) were co-cultured with GC cells, and they showed an even greater ability to inhibit ALOX15 protein expression than the control CAF exosomes without affecting ALOX15 transcription (Fig. 6h, i and j).