Based on the above findings regarding the roles of ALKBH5, YTHDF1 and miR-107 in NSCLC tumor growth and metastasis, we generated A549 cell lines stably co-expressing shALKBH5 with an empty vector (shALKBH5Vector), shYTHDF1 with shcontrol (shYTHDF1shcontrol), shALKBH5 with shYTHDF1 (shALKBH5shYTHDF1) and a control stable cell line, shcontrolVector. The gene discussed is YTHDF1; the disease is neoplasm.