The expression of syntenin was detected in non-small cell lung cancer (NSCLC) and small cell lung cancer (SCLC); the proportion of highly-expressing samples for SCLC (57.1%, 12/21) (Fig. 1c and d) was higher than that for adenocarcinoma (51.3%, 61/119) (Fig. 1e and f) and for SSC (squamous cell carcinoma) (40.8%, 20/49) (Fig. 1g and h), whereas there was no statistically significant difference in syntenin expression among SCLC, adenocarcinoma and SSC (P = 0.348). Here, SDCBP is linked to small cell lung carcinoma.