In the biopsy specimens of ESCC patients prior to NAC, high GR, Sgk1, and NDRG1 were detected in 54.7% (23/42), 45.2% (19/42), and 42.9% (18/42) of the patients examined, respectively (Table 5). Here, NDRG1 is linked to esophageal squamous cell carcinoma.