For instance, G. inflata extract has been documented to reduce spinocerebellar ataxia type 3 (SCA3) by increasing the nuclear factor erythroid 2-related factor 2-antioxidant-responsive elements (NFE2L2-ARE), coactivator 1α (PPARGC1A), and the peroxisome proliferator-activated receptor γ activities [76]. Here, NFE2L2 is linked to Spinocerebellar ataxia type 3.